Data indicating that spring football practice injuries were more than double the rate for regular-season practice led to adoption by NCAA members in 1998 of policies to address the problem; ISS subsequently has documented a 27 percent reduction in the spring football practice injury rate.

Data regarding heat illness and preseason-practice injury rates provided significant rationale for adoption in 2003 of the football preseason-acclimatization program in Divisions I, II and III.

The NCAA Committee on Competitive Safeguards and Medical Aspects of Sports and women's lacrosse committees considered head-, face- and eye-injury data in recommending mandatory eye protection in women's lacrosse for the 2004 spring season.

The NCAA Men's Ice Hockey Rules Committee relied on data indicating an increase in game-concussion injury data over the last decade in enacting stricter penalties for failure to use a mouthpiece, hitting from behind and checking into the boards.

ISS data indicating a two- to threefold increased risk of anterior cruciate ligament (ACL) injuries in women's soccer and basketball resulted in research to identify causes and develop prevention measures.

The NCAA Men's Basketball Rules Committee considered ISS data showing that a majority of game injuries occur from player contact within the free-throw lane during its recent discussions about widening the lane.

A modified ISS was used in 1992 to determine that there is less than one chance in one million exposures for HIV transmission in NCAA sports, leading to development of policies to provide reasonable and medically sound care for bleeding during competition.